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Umeki K, Shiota G, Kawasaki H

Key Research Applications in Longevity and Epigenetics Because of its stabilization, this peptide is a centerpiece in modern aging research: Epigenetic Longevity Pathways: Understanding how small peptides can influence gene expression without altering the underlying DNA sequence

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Because it avoids hepatic first-pass metabolism, circulating citrulline is primarily cleared by the proximal renal tubule, where it is enzymatically converted to arginine

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